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AOM COM Erosion of bone covering the sigmoid sinus Immune status of host Osteothrombophlebitic extension via small venules Perisinus abscessinflammation Platelets, rbcs, fibrin, wbcs adhere to inflamed area (Intact bony covering over sigmoid sinus) Inflammation of outer wall (dura) of sinus Inflammation of intima (inner wall of sinus) Mural thrombus Mural thrombus propagates, obliterating lumen Empties virulent organisms into the sigmoid sinus, resulting in septicemia Figure 236 Pathogenesis of thrombophlebitis in the sigmoid sinus.

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