See also Cleft lip and palate clinical signs, 391 cranial base dysmorphology, postnatal development, 312316 defined, 148 epidemiology, 147 post-surgical growth pattern, 404 supralaryngeal vocal tract anomalies, 477479 Isotretinoin, facial clefting, environmental factors, 168171 J Jackson-Weiss syndrome FGFR2 extracellular domain mutations, 134135 phenotype and genotype patterns, 126 Jennings genetic theory, nonsyndromic facial cleft etiology, 520521 K Kallmann syndrome, syndromic cleft classification, 22 Keratinocyte growth factor receptor (KGFR) Apert syndrome, 133 fibroblast growth factor receptors (FGFR), 126128 Kernahan, LAHSHAL labeling system, 18 21 Knockout genes craniofacialskeletal growth modification, 557558 craniosynostosis, transgenic animal studies, 217219 DiGeorge syndrome, 81 nonsyndromic facial cleft etiology, 522523 otocephalic malformations, 7172 Kyphosis, cranial base bipedalism and bracephalization, 275276 neural spatial packing, brachycephalization and, 276277 synchondrosal fusion timing, brachycephalization and, 277278 synchondrosis, comparative growth patterns, 288 INDEX 573 Optic Pathway and Striate Cortex 289 present on routine MR imaging using a standard head coil.
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